Welcome to L’AuRa: Digital Platform for Rapid POC

L’AuRa is the result of diligent discovery, state of the art nano-science and a collaborative team penchant for uncompromising precision.

Presently no rapid human diagnostic testing system can deliver central laboratory grade precision in a small mobile point of care format at the point of clinical need without sacrificing accuracy and quality. The current multi-billion dollar immuno-diagnostic marketplace relies substantially on time consuming central laboratory testing; a fifty-year old analog based technology.

LamdaGen’s L’AuRa system enables an important performance shift away from traditional ELISA based central laboratory testing to a pixel-based digital one. This digital enhancement coupled with the Company’s patented nano-based sensor technology results in remarkably enhanced sensitivity, precision and speed versus central laboratory systems.

Further, L’AuRa’s adaptive sensor systems are fully compatible with highly miniaturized mobile or POCT devices. The powerful detection systems are easily configured into highly robust and miniaturized, handheld or other near-patient and near-consumer configurations, depending on targeted application and desired form factor.

The simplicity and inherent mobility of LamdaGen’s sensor technology enables advanced systems that fulfill the unmet global market need for precise clinical or consumer oriented, rapid “on the spot” mobile POC testing as defined by:

  • Rapid real-time results
  • High analytical sensitivity with quantitative precision
  • Simplicity and ease of use
  • Single or multiplexed targets

Beyond human clinical health, L’AuRa’s tiny digital sensing systems are also well suited for high value application in industrial or consumer oriented food safety, companion animal and animal food stock, and certain environmental health applications – where point of use can literally be anywhere.

The L’Aura system is economical, easy to use, scalable and ideal for tiny multiplex and multi-panel applications. L’AuRa is also compatible with any biomarker, including newly identified low-abundance ones.

For information and details about L’AuRa please email: L.AuRa@lamdagen.com

 
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L’AuRa enables next-generation decentralized diagnostic precision – outside the walls of the hospital

The L’AuRa digital system is particularly well suited for critical care settings such as ER’s, ICU’s and first responder units, as well as for integrated testing in clinics, urgent care facilities, physician offices, pharmacies, mobile/field and in-home patient monitoring.

L’AuRa enables laboratory grade diagnostic performance for modern POC and mobile systems. This transition opens the globally connected doorway to decentralized mobile and precise testing for earlier detection, treatment and prevention of disease.

LamdaGen licenses its patented and proprietary technologies and sensing systems on an open architecture basis to companies for integration into their existing diagnostic systems and devices, or into advanced POC or adaptive mobile/wearable products in development.

LamdaGen has optimized L’AuRa’s performance to clinical levels for many targets including:

L'AuRa for high performance, rapid and mobile POC diagnostics

L’AuRa for rapid and precise POC and mobile diagnostics

 

Cortisol

L’AuRa and Precise Cortisol Quantification in a Single-Step 15 Minute Assay
A biomarker indicative of the body’s response to stress

Cortisol:

  • In healthy humans, cortisol production follows a personal rhythm, peaking in early morning and dropping to the lowest concentration at night. In response to stress, cortisol levels rise independently of the circadian cycle.
  • Prolonged periods of irregular cortisol levels are well-evidenced to have negative impacts on mental, physical and emotional performance and well being (1, 2).
  • Dose response curve (shown right) for saliva-based cortisol quantitation in a competitive 15-minute assay format using LamdaGen’s L’AuRa digital platform.
  • Each data point represents the average of 5 repeats
  • The assay range is between 50 pg/mL – 5 ng/mL
  • The recovery yield percentages range from 92% to 110%, with an average of 101%

1. L.D. Dorn et al., Salivary cortisol reflects serum cortisol: analysis of circadian profiles, Ann Clin Biochem 44, 281-284 (2007)

2. E. Aardal & A Holm, Cortisol in saliva – reference ranges in relation to cortisol in serum, Eur J Clin Chem Clin Biochem 33(12) 81-94 (1995)